Getting relief from OA knee pain

Treatment of OA knee pain

There are several things you can do to help reduce knee pain due to OA.

Lifestyle changes

  • Losing a bit of weight, if you are overweight, to alleviate some of the stress on your knees
  • Practicing low impact exercises (e.g. walking, biking, swimming) to strengthen your muscles
  • Resting when you experience any pain or swelling in your knee
  • Applying heat or ice to reduce knee pain


Over-the-counter painkillers like acetaminophen can help reduce pain. Your doctor might also recommend ibuprofen or topical medications to soothe aching knee joints. If your condition escalates, non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin may be prescribed to relieve the pain and inflammation.


Viscosupplementation, such as Cingal™, Monovisc® or Orthovisc®, is the injection of a clear gel-like substance containing hyaluronic acid.

A single injection of Cingal™ and Monovisc® or three injections of Orthovisc® can help alleviate OA knee pain while increasing the flexibility and mobility of your knee. In addition, the corticosteroid found in Cingal™ can relieve pain rapidly.

Hyaluronic acid is a naturally occurring substance found in the synovial fluid of the knee joint. The injection of hyaluronic acid into the joint is thought to lubricate the cartilage (much like oil lubricates an engine), thereby reducing pain.

Corticosteroid injections

Corticosteroid (or cortisone) injections like Cingal™ may be used to relieve pain from OA of the knee by reducing swelling of the joint. Relief is often felt quickly following an injection and can last from a few days to a couple months, depending on individuals. Most injections typically take 24–48 hours to take full effect.

Combination viscosupplementation and corticosteroid injection

A combination viscosupplementation and corticosteroid treatment like Cingal™ is a single intra-articular injection that provides the long term pain relief of a viscosupplement (a clear gel-like substance containing hyaluronic acid) with the quick pain relief of a corticosteroid. Cingal™, the one and only combination treatment, offers the best of both worlds.

The patient literally hobbled in and, after using Cingal™, made her physician cry because she said it meant so much to her that she could bend her knee.


Knee replacement surgery is a last resort option for patients with OA pain that cannot be relieved by the above-mentioned options. The decision to perform surgery depends on many factors, including pain tolerance, disability and the risks and benefits of surgery.

Hear what experts have to say

Cingal™, Monovisc®, and Orthovisc are options which can provide relief from OA knee pain.

Timothy Deakon

  • Director, Oakville Sports Injury Clinic
  • Staff Surgeon, Oakville Trafalgar Memorial Hospital
  • Team Orthopedic Surgeon, Toronto Argonauts Football Team

Acces our private insurance coverage guide for reimbursement information on Cingal™, Monovisc® and Orthovisc®

Download our brochures on OA knee pain and treatment with Cingal™ and Monovisc®

Copyright © 2017 Pharmascience Inc. Montreal, H4P 2T4 Canada. All rights reserved.

CingalTM, Monovisc® and Orthovisc® may not be suitable for everyone. Talk to your doctor if you have questions regarding these products, or for more information on pain associated with osteoarthritis of the knee. Product information is only pertinent for use in Canada. CingalTM, Monovisc® and Orthovisc® are trademarks of Anika Therapeutics Inc., used under licence by Pharmascience Inc. Pendopharm, Division of Pharmascience Inc. Product Licences are pertinent to use in Canada. Product Licences herein are not approved for use in the U.S.